Exon array analysis reveals neuroblastoma tumors have distinct alternative splicing patterns according to stage and MYCN amplification status

Table 1 Tumor samples used in the study

	Year of Diagnosis	Age at Diagnosis (years)	INSS Stage	*MYCN*Amplification Status	Clinical Outcome	Years of Survival
NB7	1998	1.3	1	NA	A	5.2
NB8	1998	4.6	4	NA	D	1.8
NB9	1996	1.1	1	NA	A	7.1
NB17	2000	1.2	1	NA	A	3.5
NB21	2000	5.2	4	AMP	D	0.6
NB24	2000	0.6	4	NA	A	3
NB27	2000	10.5	4	AMP	D	1.4
NB29	1998	0.3	1	NA	A	5.1
NB30	1997	0.9	4	NA	A	5.9
NB31	1998	1.4	4	NA	A	6.7
NB32	1998	1.2	4	NA	A	5.7
NB33	1998	1.4	1	NA	A	4.8
NB34	1997	1.2	1	NA	A	5.2
NB205	1995	3.9	4	NA	D	2.3
NB206	1995	2.7	4	NA	D	5.8
NB207	1995	4.4	4	NA	D	3.1
NB208	1995	0.8	1	NA	A	4.8
NB210	1996	2.5	4	NA	D	1.1
NB221	1997	0.4	1	NA	A	5.7
NB237	1999	4.0	1	NA	A	3.2
NB238	1999	1.1	1	NA	A	3
NB265	1996	1.8	4	AMP	D	2
NB266	1996	2.0	4	AMP	D	0
NB269	1997	0.8	4	NA	A	5.3
NB275	1995	1.6	4	NA	D	1
NB278	1999	1.7	4	AMP	D	0.8
NB282	1999	4.6	4	NA	A	3.3
NB283	1999	5.5	4	NA	D	4
NB500	1995	5.1	4	NA	A	7.4
NB503	2000	3.9	4	NA	A	3.3
NB504	2000	0.3	4	NA	A	3.5
NB506	2000	0.3	4	NA	A	3.9
NB508	2000	0.2	4	NA	A	3.2
NB509	2000	3.0	4	NA	D	4.1
NB510	2000	0.6	4	NA	A	3.4
NB511	2001	0.1	4	NA	A	3.0
NB514	2001	11.6	4	NA	A	3.5
NB515	2001	3.9	4	NA	A	3.2
NB521	1999	1.5	4	NA	A	5.6
NB536	1998	3.1	4	NA	D	1.2
NB540	1999	3.4	4	NA	D	1.1
NB541	1999	9.6	4	AMP	D	0.1
NB543	1999	11.4	4	NA	D	1.4
NB545	1999	3.4	4	AMP	D	2.2
NB547	2000	1.5	4	AMP	D	3.8
NB548	2000	1.6	4	NA	D	3.4
NB581	2002	1.6	4	AMP	D	1.6

Abbreviations: INSS, International Neuroblastoma Staging System; AMP, amplification; NA, not amplified; A, alive without event; D, deceased due to neuroblastoma disease.

ISSN: 1755-8794