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Table 3 GO terms corresponding to the "biological process" ontology significantly associated to chromosomal regions frequently lost in the glioblastomas [30].

From: A large scale survey reveals that chromosomal copy-number alterations significantly affect gene modules involved in cancer initiation and progression

GO term

GO ID

p-value

(FDR-adjusted)

p-value

(Bonferroni-adjusted)

sensory perception of chemical stimulus

GO:0007606

9.83 × 10-24

1.97 × 10-17

sensory perception

GO:0007600

2.39 × 10-17

7.17 × 10-14

neurological process

GO:0050877

4.45 × 10-12

1.78 × 10-06

G-protein coupled receptor protein signaling pathway

GO:0007186

5.44 × 10-8

0.0272

chromatin assembly

GO:0031497

1.60 × 10-5

0.000799

chromatin assembly or disassembly

GO:0006333

1.85 × 10-5

0.00011

cell surface receptor linked signal transduction

GO:0007166

0.00028

0.00169

DNA packaging

GO:0006323

0.00204

0.01740

establishment and/or maintenance of chromatin architecture

GO:0006325

0.00204

0.02042

protein-DNA complex assembly

GO:0065004

0.00204

0.01926

chromosome organization and biogenesis (sensu Eukaryota)

GO:0007001

0.00217

0.02389

chromosome organization and biogenesis

GO:0051276

0.00234

0.02819

lipid metabolic process

GO:0006629

0.02525

0.17675

gas transport

GO:0015669

0.02628

0.15771

oxygen transport

GO:0015671

0.02628

0.15771

organelle organization and biogenesis

GO:0006996

0.03449

0.41390

regulation of liquid surface tension

GO:0050828

0.04568

0.04568

  1. The one-tailed test, as implemented in the GSA version provided by the Babelomics package [44], was used (see details in [14]). Nominal p-values were adjusted for multiple testing using the FDR [34] and the Bonferroni methods.