Figure 2From: Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome Microarray analysis. Retinal RNA from control (n = 8), diabetic (n = 5) and insulin-treated diabetic (n = 7) rats collected after the 3 months experimental paradigm were analyzed by Illumina Rat Ref12 microarray. 11,040 of 22,523 probes on the microarray had detectable signals. The 1,376 probes determined to be differentially expressed (P < 0.05, |fold change| >1.2) between control and diabetic animals were clustered according to expression in the insulin-treated diabetic group into Not Normalized, Partially Normalized, Normalized, and Inverted expression groups.Back to article page