Table 2 Identification of miRNA targets from 15 down-regulated and 71 up-regulated mRNAs
From: Modeling microRNA-mRNA Interactions Using PLS Regression in Human Colon Cancer
Cancer-related and down-regulated miRNA | miRNA family | No. of target mRNAs | No. (%) of overlapping PLS predicted mRNAs with TargetScan5.1 | No. (%) of overlapping PLS predicted mRNAs with miRanda |
|---|---|---|---|---|
hsa-let-7 g | Let-7 g | 16 | 0 | 2(12.5) |
hsa-miR-101 | miR-101 | 7 | 0 | 0 |
hsa-miR-133a | miR-133 | 17 | 3(17.6) | 2(11.8) |
hsa-miR-150 | miR-150 | 20 | 3(15.0) | 1(5.0) |
hsa-miR-15a | miR-15 | 8 | 1(12.5) | 1(12.5) |
hsa-miR-16 | miR-16 | 8 | 1(12.5) | 0 |
hsa-miR-29b | miR-29 | 15 | 3(20.0) | 2(13.3) |
hsa-miR-29c | miR-29 | 7 | 2(28.6) | 1(14.3) |
hsa-miR-30a | miR-30 | 22 | 3(13.6) | 3(13.6) |
hsa-miR-30b | miR-30 | 20 | 4(20.0) | 2(10.0) |
hsa-miR-30c | miR-30 | 15 | 1(6.7) | 1(6.7) |
hsa-miR-30d | miR-30 | 25 | 7(28.0) | 5(20.0) |
hsa-miR-30e | miR-30 | 17 | 3(17.6) | 3(17.6) |
hsa-miR-34b | miR-34 | 12 | 3(25.0) | 0 |
mmu-miR-342 | miR-342 | 21 | 4(19.0) | 1(4.8) |
Total | - | - | 16.5 | 11.0 |