From: Modeling microRNA-mRNA Interactions Using PLS Regression in Human Colon Cancer
Cancer-related and down-regulated miRNA | miRNA family | No. of mRNAs | GO terms |
---|---|---|---|
hsa-let-7 g | Let-7 g | 16 | Anaphase-promoting complex(APC)-dependent proteasomal ubiquitin-dependent protein catabolic process, response to oxidative stress and regulation of apoptosis |
hsa-miR-101 | miR-101 | 7 | Ubiquitin-dependent protein catabolic process, APC-dependent proteasonmal ubiquitin-dependent protein catabolic process and oxidoreductase activity |
hsa-miR-133a | miR-133 | 17 | Polyamine biosynthetic process,glutathione peroxidase process, Ubiquitin-dependent protein catabolic process and regulation of apoptosis |
hsa-miR-150 | miR-150 | 20 | Polyamine biosynthetic process, APC-dependent proteasomal ubiquitin-dependent protein catabolic process, Glutathione peroxidase activity |
hsa-miR-15a | miR-15 | 8 | Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, response to oxidative stress and proteasome complex |
hsa-miR-16 | miR-16 | 8 | APC-dependent proteasomal ubiquitin-dependent protein catabolic process, negative regulation of cell proliferation and oxidoreductase activity |
hsa-miR-29b | miR-29 | 15 | Regulation of cell proliferation, glutathione peroxidase activity and regulation of apoptosis |
hsa-miR-29c | miR-29 | 7 | Ubiquitin-dependent protein catabolic process, APC-dependent proteasomal ubiquitin-dependent protein catabolic process and translational elongation |
hsa-miR-30a | miR-30 | 22 | Polyamine biosynthetic process, ubiquitin-dependent protein catabolic process, and regulation of apoptosis |
hsa-miR-30b | miR-30 | 20 | Ubiquitin-dependent protein catabolic process, polyamine biosynthetic process and oxidative stress |
hsa-miR-30c | miR-30 | 15 | Polyamine biosynthetic process, ubiquitin-dependent protein catabolic process, and regulation of apoptosis |
hsa-miR-30d | miR-30 | 25 | Regulation of apoptosis, glutathione peroxidase activity and ubiquitin-dependent protein catabolic process |
hsa-miR-30e | miR-30 | 17 | Polyamine biosynthetic process, response to oxidative stress and regulation of apoptosis |
hsa-miR-34b | miR-34 | 12 | Regulation of cell proliferation, oxidoreductase activity and translational elongation |
mmu-miR-342 | miR-342 | 21 | Polyamine biosynthetic process, translational elongation and APC-dependent proteasomal ubiquitin-dependent protein catabolic process |