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Figure 2 | BMC Medical Genomics

Figure 2

From: Distinct DNA methylation epigenotypes in bladder cancer from different Chinese sub-populations and its implication in cancer detection using voided urine

Figure 2

DNA Methylation profiles from different Chinese sub-populations. A. The histogram showed that methylation of p14, IRF8, APC, hMLH1, SOCS-1 and E-cadherin varied among different Chinese sub-populations. * and ** denote P < 0.05 and P < 0.01 respectively (Mann-Whitney U). B, Histogram showing the number of patients against the number of genes methylated concurrently. Samples from Taiwan and China displayed bimodal distribution which is a characteristic of CpG island methylator phentotype (CIMP). C. Dichotomous heat map of the DNA methylation data from different Chinese sub-populations. Black, orange and blue blocks represented methylated loci from Taiwan, Hong Kong and China respectively. Red bars indicated MI-high populations (≥5 genes showing concurrent methylation) and green bars indicated MI-low populations.

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BMC Medical Genomics

ISSN: 1755-8794

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