Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival

Table 6 Genes that have a cohort-dependent association (P-value < 0.05) with the overall glioblastoma survival

Gene Symbol	Probe Identifier	Clinical Cohort	P-value	Level of Clinical Cohort	Hazard Ratio¹	Relevant literature references
Polr2d	214144_at	Therapy	0.0044	Other	0.35 (0.18-0.70)	[117]^O
				R	0.50 (0.31-0.81)
				CRT	0.68 (0.38-1.21)
				None	0.77 (0.43-1.39)
				CRnoT	0.93 (0.58-1.5)
Igf2bp3	203820_s_at	Gender	0.0146	Female	1.02 (0.84-1.24)	[118]^O
				Male	1.29 (1.12-1.49)

n/a, No association with any type of cancer found in literature;
¹ Hazard ratio estimate (95% confidence interval);
^G Gene confirmed in an independent glioblastoma multiforme study; the number between square brackets denotes the corresponding literature reference;
^O Gene confirmed in an independent study on any other type of cancer; the number between square brackets denotes the corresponding literature reference.

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