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Table 8 Genes that have a cohort-dependent association (P-value < 0.05) with progression-free glioblastoma survival

From: Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival

Gene Symbol Probe Identifier Clinical Cohort P-value Level of Clinical Cohort Hazard Ratio1 Relevant literature references
Gdf10 206159_at Gender 0.0317 Male 0.37 (0.23-0.60) n/a
     Female 0.80 (0.45-1.42)  
Vav3 218807_at Race 0.008 Other 0.41 (0.29-0.59) [81]G
     White 0.68 (0.55-0.85)  
Rps20 216246_at Race 0.0003 Other 0.75 (0.39-1.44) [75]O
     White 1.83 (1.03-3.24)  
Rab31 217764_s_at Race <.0001 White 1.47 (0.93-2.30) [74]O
     Other 7.72 (3.71-16.07)  
Apool 213289_at Therapy 0.0026 R 1.64 (1.13-2.38) [131]O
     None 1.93 (0.63-5.98)  
     CRnoT 2.23 (1.55-3.20)  
     Other 3.86 (1.83-8.13)  
     CRT 4.82 (2.69-8.63)  
  1. n/a, No association with any type of cancer found in literature;
  2. 1 Hazard ratio estimate (95% confidence interval);
  3. G Gene confirmed in an independent glioblastoma multiforme study; the number between square brackets denotes the corresponding literature reference
  4. O Gene confirmed in an independent study on any other type of cancer; the number between square brackets denotes the corresponding literature reference.