Figure 2From: A genome-wide DNA methylation study in colorectal carcinoma Overlap of results from different normalization methods. Venn diagram showing overlap between the lists of differentially methylated autosomal loci identified by ANOVA models from four different normalization procedures- (a) no normalization of signal intensity, no normalization of β-values- right lower ellipse (n = 724) (b) no normalization of signal intensity to calculate β-values initially, but subsequently quantile normalization of β-values- right upper ellipse (n = 632); (c) background normalization of signal intensity to calculate β-values, but no normalization of β-values- left upper ellipse (n = 852) and (d) background normalization of signal intensity to calculate β-values, and quantile normalization of β-values- left lower ellipse (n = 759).Back to article page