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Table 3 GWA SNPs with confirmed allelic association with obesity in extension studies

From: Genome wide association study identifies KCNMA1contributing to human obesity

Chr. Gene Effect allele* Cohort** Call rate (%) Obese   Controls   P§§
      GG/GT/TT GG/GT/TT  
10 KCNMA1 rs2116830G 1 98 121/35/4 87 91/59/9 76 5.0 × 10-04
    2 99 314/126/9 84 153/74/13 79 0.019
    3 99 1232/499/53 83 1108/522/61 81 0.018
    4 98 684/232/25 85 348/161/16 82 0.024
    5 97 598/263/26 82 1065/576/81 79 0.0017
    6 100 318/125/9 83 295/128/12 84 0.35
    Pooled   3267/1180/126   3060/1520/192   2.8 × 10-10
11 BDNF rs988712G 1 91 104/53/4 81 86/67/10 73 0.0017
    2 99 300/140/13 82 139/83/16 76 0.0095
    3 99 1126/590/66 80 976/595/112 76 3.9E-05
    4 98 609/283/34 81 273/199/50 71 2.2 ×10-9
    5 95 540/290/41 79 942/642/106 75 0.0019
    6 99 273/148/25 78 246/151/33 75 0.13
    Pooled   2952/1504/183   2662/1737/327   5.2 × 10-17
  1. * All SNPs are in HWE with P> 0.05. ** Details about cohorts are given in table 1. § Frequency of effect allele among obese cases and controls. §§ Allele frequencies were compared by Chi2-test.