A computational procedure for functional characterization of potential marker genes from molecular data: Alzheimer's as a case study

Table 7 Table of the integrated functional analysis for the three signatures

KEGG pathway	KEGG Category	Protein	GSE1297	GSE5281
Cytokine-cytokine receptor interaction		●		o
Neuroactive ligand-receptor migration	Signaling Molecules and Interaction	o	o	o
ECM-receptor interaction			●	o
Antigen processing and presentation			o	o
Hematopoietic cell lineage	Immune System	●	o	o
Leukocyte transendothelial migration		o		o
MAPK signaling pathway	Signal Transduction	●	o	o
Focal adhesion	Cell Communication	o	o	o

KEGG pathways common between two or three signatures. The table reports the pathway name, its KEGG category and the signatures IDs. The enriched pathways are identified with filled circles, whereas empty circles are associated to not enriched pathways.

ISSN: 1755-8794