Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancer

Kompass, Kenneth S; Witte, John S

doi:10.1186/1755-8794-4-6

Table 2 Top scoring creQTLs at a significance threshold of q = 5.50 × 10^-4.

From: Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancer

Locus	dbSNP	Location (bp)	Position	Gene Symbol	Gene Title	q_creQTL
chr6q16	rs959186	125994	downstream	RNGTT	RNA guanylyltransferase and 5'-phosphatase	1.13 × 10-4
chr13q12.3-q13	rs9315215	348455	upstream	RFC3	replication factor C (activator 1) 3, 38 kDa	1.13 × 10-4
chr13q12-q13	rs9315215	183849	upstream	STARD13	StAR-related lipid transfer (START) domain containing 13	1.13 × 10-4
chrXq21.33	rs4969656	695921	upstream	DIAPH2	diaphanous homolog 2 (Drosophila)	1.93 × 10-4
chrXq21.3-q22	rs4969656	2315179	upstream	NAP1L3	nucleosome assembly protein 1-like 3	1.93 × 10-4
chr3q13.1	rs4856121	2246645	upstream	ALCAM	activated leukocyte cell adhesion molecule	1.93 × 10-4
chr5q31-q32	rs319217	0	intron	PPP2R2B	protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform	1.13 × 10-4
chr1p31.1	rs2296697	0	intron	LPHN2	latrophilin 2	5.40 × 10-4
chr2p21	rs222471	31099	downstream	KCNG3	potassium voltage-gated channel, subfamily G, member 3	4.91 × 10-4
chr2p21	rs222471	49701	upstream	COX7A2L	cytochrome c oxidase subunit VIIa polypeptide 2 like	4.91 × 10-4
chr4q21	rs1992489	59023	upstream	CXCL13	chemokine (C-X-C motif) ligand 13	5.19 × 10-4
chr4q21.1	rs1992489	282671	downstream	CCNG2	cyclin G2	5.19 × 10-4
chr14q13-q21	rs1951319	680177	downstream	RPL10L	ribosomal protein L10-like	5.48 × 10-4
chr14q21.2	rs1951319	717439	upstream	C14orf106	chromosome 14 open reading frame 106	5.48 × 10-4
chr8p23.2	rs1714757	0	intron	CSMD1	CUB and Sushi multiple domains 1	1.47 × 10-4
chr16p13.12	rs1159167	147599	upstream	ERCC4	excision repair cross-complementing rodent repair deficiency, complementation group 4	4.91 × 10-4
chr16p13.12	rs1159167	968670	upstream	CPPED1	calcineurin-like phosphoesterase domain containing 1	4.91 × 10-4
chr22q12.1	rs10483151	0	intron	TTC28	tetratricopeptide repeat domain 28	1.81 × 10-4

Associated gene clusters have been omitted for brevity and are listed in Additional File 1. 'Position' and 'Location (bp)' as for Table 1; q _creQTL' indicates FDR-adjusted significance.

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