Figure 2

RNA-Seq and Sanger sequencing of WWC1-ADRBK2. We identified an in-frame gene fusion transcript in HCC1315: (A) schematic of the predicted gene fusion illustrating RNA-Seq evidence that support the fusion between exon 19 of WWC1 and exon 10 of ADRBK2. Reads are indicated by black solid lines. Paired reads are indicated by the dotted line joining two reads. Reads that span across the fusion junction are highlighted by red solid lines; and (B) the fusion junction was verified using Sanger sequencing of cDNA.