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Table 2 Summary of candidate gene fusions identified by paired end RNA-Seq

From: Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines

Sample PEFS >0 PEFS>= 5 PEFS>= 5 plus junction spanning reads
SUM149PT 1 1 1
SUM1315O2 20 2 0
HCC3153 8 1 1
T92 13 0 0
T50 1090 2 1
T160 437 4 1
HCC2337 14 2 0
MCF10A 10 0 0
  1. In order to prioritize gene fusion candidates with the most read support, we selected candidates with a minimum PEFS of 5 for further investigation. A total of 12 gene fusion candidates with a PEFS >= 5 were identified based on discordantly aligned paired reads. Of these, four candidates (33%) were further found to have supporting reads spanning the exon-exon fusion junction.