Analysis of BMP4 and BMP7 signaling in breast cancer cells unveils time-dependent transcription patterns and highlights a common synexpression group of genes

Table 4 Summary of the temporal clusters obtained from the analysis of BMP7 data.

	Early		Early-intermediate		Late-intermediate		Late		Undetermined
	cluster ID	genes/cluster	cluster ID	genes/cluster	cluster ID	genes/cluster	cluster ID	genes/cluster	cluster ID	genes/cluster
HCC1954	2	32	4	66	3	226	1	197	6	119
(14 clusters)	5	324	12	113	10	116			13	113
	7	113	14	149
	8	35
	9	275
	11	111
Total		890		328		342		197		232
MDA-MB-231	6	97	4	41	2	175	1	335
(16 clusters)	7	27	9	120	5	321	3	512
	10	108	11	101	16	144	8	140
	12	125	14	147
	13	52	15	85
Total		409		494		640		987
MDA-MB-361	7	240	2	177	1	379	6	252
(12 clusters)	8	193	3	235	5	328
	11	258	4	230	9	58
			10	336	12	73
Total		691		978		838		252
T-47D	2	767	8	212	1	183	5	1265	14	7
(14 clusters)	3	127	9	594	10	377	6	559
	4	38	12	476
	7	414
	11	163
	13	88
Total		1597		1282		560		1824		7
ZR-75-30	3	205	2	169	11	105	14	87	1	8
(22 clusters)	5	286	4	30	12	196			7	16
	13	114	6	1544					9	37
	15	216	8	35					17	23
	20	250	10	1493					21	14
	22	36	16	147
			18	85
			19	336
Total		1107		3839		301		87		98

Gene clusters were classified in four temporal categories (early, early-intermediate, late-intermediate and late). Clusters with unclear profiles were classified as undetermined. The cluster ID column contains the ID number of the cluster.

ISSN: 1755-8794