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Table 1 Clinical characteristics.

From: Transforming growth factor β receptor 1 is a new candidate prognostic biomarker after acute myocardial infarction

  Test cohort Validation cohort
  High EF Low EF P value   
  (n = 16) (n = 16) (high vs low EF) (n = 115)
4-months EF, % (median-range) 63 45-73 35 20-40 0.0003 40 15-86
Age, y (median-range) 56 43-84 68 38-83 0.57 56 32-90
Sex (male, n, %) 13 81% 13 81% 1 98 85%
Body Mass Index (median-range) 28 23-35 26 20-38 0.25 27 19-43
Serum markers (median-range)        
   Troponin T (ng/mL) 0.78 0.06-10.69 11.64 1.46-26.1 0.007 4.76 0.03-26.1
   CPK (units/L) 762 603-3798 4860 1015-9383 < 0.001 1978 602-9383
Cardiovascular history, n (%)        
   Prior MI 2 13% 3 19% 0.64 7 6%
   CABG 0 0% 1 6% 0.33 3 3%
   PTCA 1 6% 2 13% 0.56 11 10%
   Diabetes 4 25% 6 38% 0.46 22 19%
   Hypertension 6 38% 7 44% 0.73 47 41%
   Hypercholesterolemia 7 44% 9 56% 0.50 45 39%
   Tobacco 4 25% 5 31% 0.71 53 46%
Medications, n (%)        
   Beta-blockers 16 100% 14 88% 0.16 98 85%
   Calcium antagonists 3 19% 0 0% 0.08 0 0%
   Nitrates 6 38% 6 38% 1 31 27%
   ACE inhibitors 10 63% 10 63% 1 51 44%
   Statins 14 88% 14 88% 1 89 77%
   Angiotensin receptor inhibitors 2 13% 0 0% 0.16 1 1%
  1. All MI patients had successful mechanical reperfusion and stenting of the infarct artery within 12 hours of chest pain onset. All patients received Aspirin, Clopidogrel, Heparin and Abciximab in the presence of a large thrombus.
  2. ACE: Angiotensin Converting Enzyme; CABG: Coronary Artery Bypass Grafting; EF: Ejection Fraction; PTCA: Percutaneous Transluminal Coronary Angioplasty; MI: Myocardial Infarction.