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Table 2 Subsets of angiogenic genes associated with LV function.

From: Transforming growth factor β receptor 1 is a new candidate prognostic biomarker after acute myocardial infarction

Cluster Protein number Interaction number MCODE score* Genes
1 3 4 1 TGFBR1, TGFBR2, CLU
2 5 7 1 TGFBR1, TGFBR2, CLU, MAP3K7, FOS
3 10 16 1.3 TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1
4 12 20 1.42 TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1,
5 13 22 1.38 TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, PTGS2
6 16 27 1.37 TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, PTGS2, FYN, LCK, CD55
7 21 34 1.38 TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, PTGS2, FYN, LCK, CD55, ATP5B, SRC, MYOC, ANXA2, PLG
8 28 44 1.32 TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, PTGS2, FYN, LCK, CD55, ATP5B, SRC, MYOC, ANXA2, PLG, SOD1, BCL2, MAPK14, SMAD7, SHC1, MME, ADM
9 35 55 1.34 TGFBR1, TGFBR2, CLU, MAP3K7, FOS, SUMO4, STAT1, PTK2, BMX, CAV1, ITK, PAK1, PTGS2, FYN, LCK, CD55, ATP5B, SRC, MYOC, ANXA2, PLG, SOD1, BCL2, MAPK14, SMAD7, SHC1, MME, ADM, CFH, THBS1, KNG1, PLAUR, PRKCA, RAB25
  1. *MCODE cluster score = density * number of nodes.