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Figure 1 | BMC Medical Genomics

Figure 1

From: Interaction among apoptosis-associated sequence variants and joint effects on aggressive prostate cancer

Figure 1

Visualization of the interaction among apoptosis-related sequence variants using Statistical Epistasis Network Modeling (SEN)-guided MDR. The Statistical Epistasis Network (SEN) was generated using a pairwise interaction strength cut-off or 1%. Overall, the model has 91 vertices (single SNPs), 80 edges (pairwise SNPs), and 18 components ("sub-networks" of vertices and edges). The largest connected component, shown in the center and spanning the entire length of this model, has 24 vertices and 34 edges. Each number in Figure 1 corresponds with a specific apoptosis-related SNP analyzed in the current study, as summarized in Additional file 2.

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