Skip to main content

Table 3 Reclassification improvement in new prediction models versus current PCT alone model

From: Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children

New model Summary NRI (95% CI), p-value NRI for events (95% CI), p-value NRI for non-events (95% CI), p-value
PCT + Resistin 0.50 (0.17, 0.83), 0.0032 −0.04 (−0.22, 0.12), 0.6015 0.54 (0.26, 0.82), 0.0002
PCT + NGAL 0.58 (0.29, 0.86), 0.0001 0.01 (−0.15, 0.18), 0.8690 0.56 (0.32, 0.79), <0.0001
PCT + Resistin + NGAL 0.81 (0.45, 1.16), <0.0001 0.14 (−0.06, 0.33), 0.1700 0.67 (0.38, 0.97), <0.0001
  1. Event = SBI, non-event = not SBI.