Table 2 Minimal common regions of recurrent (≥ 25%) copy number amplification and deletion
From: Identification of genes with a correlation between copy number and expression in gastric cancer
Aberration | Position (Mb) | Size (Mb) | Frequency, n = 27 (%) | Possible target genes |
|---|---|---|---|---|
+1q42.3 | 233.85-233.86 | 0.02 | 7 (26%) | - |
+6p21.1 | 43.41-44.34 | 0.94 | 8 (30%) | MRPL14, POLR1C, HSP90AB1, XPO5, MRPS18A |
+6p12.2 | 52.22-52.43 | 0.20 | 7 (26%) | MCM3 |
+6p12.2-p12.1 | 52.44-52.98 | 0.54 | 7 (26%) | TMEM14A |
+7p21.1 | 16.68-17.28 | 0.60 | 8 (30%) | BZW2 |
+7p12.2 | 50.62-50.67 | 0.05 | 7 (26%) | - |
+7p12.1-p11.1 | 53.84-57.47 | 3.63 | 9 (33%) | MRPS17, CCT6A |
+7q11.21-q11.23 | 63.35-73.62 | 10.27 | 9 (33%) | CLDN4, EIF4H, SBDS, WBSCR22 |
+7q11.23 | 73.63-75.81 | 2.18 | 9 (33%) | MDH2 |
+7q21.12-q21.13 | 87.54-90.07 | 2.52 | 7 (26%) | SRI, CLDN12 |
+7q21.2 | 91.91-92.53 | 0.62 | 7 (26%) | - |
+7q21.3-q22.1 | 97.67-100.86 | 3.19 | 9 (33%) | PLOD3, POP7, ARPC1A, COPS6, BUD31 |
+8p11.21-q11.1 | 42.35-47.79 | 5.44 | 8 (30%) | VDAC3 |
+8q11.1-q24.3 | 47.86-146.27 | 98.41 | 19 (70%) | * |
+13q13.3 | 39.19-39.28 | 0.10 | 7 (26%) | - |
+13q14.11 | 39.81-40.58 | 0.77 | 8 (30%) | - |
+20p13 | 0.19-0.71 | 0.52 | 7 (26%) | - |
+20p12.1-p11.23 | 17.53-17.98 | 0.46 | 8 (30%) | - |
+20p11.21 | 24.84-25.35 | 0.51 | 10 (37%) | - |
+20q11.21-q12 | 29.40-40.53 | 11.12 | 14 (52%) | TPX2, RPN2, POFUT1, CHMP4B, TOP1 |
+20q12-q13.2 | 40.54-52.12 | 11.57 | 11 (41%) | CTSA, SLPI, MYBL2, PI3, YWHAB, TOMM34, B4GALT5, PIGT, C20orf111 |
+20q13.33 | 57.96-62.15 | 4.19 | 10 (37%) | PSMA7, C20orf11 |
−3p14.2 | 60.42-60.48 | 0.06 | 7 (26%) | - |
−6p25.3 | 1.86-2.02 | 0.16 | 9 (33%) | - |
−18q22.1 | 60.04-60.07 | 0.02 | 7 (26%) | - |