β-tubulin index predicts response to docetaxel chemotherapy. A) Experimental strategy to identify the β-tubulin index. B) β-tubulin co-expressed probesets within the three discovery cohorts. C) Experimental strategy to validate the β-tubulin index. D) ROC analysis of β-tubulin index scores and response to docetaxel neoadjuvant chemotherapy (AUC: 0.89, p = 0.002). E) β-tubulin index scores in patients that experienced pCR or had RD after neoadjuvant chemotherapy ( p < 0.0001, t-test).