BMC Medical Genomics

Table 3 Characteristics of the validation cohorts

From: A target based approach identifies genomic predictors of breast cancer patient response to chemotherapy

Characteristic	GSE21094		GSE25055		GSE25065		GSE22513
	#	%	#	%	#	%	#	%
# patients	278		310		198		14
Age, years							NA
<=50	133	48	168	54	109	55
>50	144	52	142	46	89	45
NA	1	0
Mean	52		50		49
STD	11		10		11
Nodal status	NA						NA
Positive			223	72	128	65
Negative			87	28	71	35
NA
Grade	NA						NA
1			19	6	13	7
2			117	38	63	32
3			151	49	108	55
NA			23	7	14	7
Response
pCR	56	20	58	19	42	21	4	29
RD	222	80	248	80	140	71	10	71
NA			4	1	16	8
ER status							NA
Positive	164	49	131	42	123	62
Negative	114	41	174	56	74	37
NA			5	2	1	1

Abbreviations: STD: Standard deviation; pCR: complete pathological response; RD: Residual disease. ER: Estrogen receptor; NA: Not available.

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ISSN: 1755-8794

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