Molecular prediction for atherogenic risks across different cell types of leukocytes

BMC Medical Genomics

Table 1 Microarray datasets were used for atherosclerosis prediction model derivation and evaluation.

Data Set	Human Blood Cell	Function	GEO ID	Disease information	Samples
FH1	Monocyte	Training	GSE6054	Familial Hypercholesterolemia	23
FH2	Circulating T cells	Test	GSE6088	Familial Hypercholesterolemia	23
FH3	White Blood cells	Test	GSE13985	Familial Hypercholesterolemia	10
ATHERO1	Macrophage	Test	GSE9874	Patient with subclinical atherosclerosis and a family history of coronary heart disease	28

Four previously-published microarray sets in the NCBI GEO database (http://www.ncbi.nlm.nih.gov/geo) from different human blood cells were used to construct and validate our prediction model. Data set FH1 was chosen and used for our multi-gene model development. The other three sets---FH2, FH3, and ATHERO1---were used for evaluation of the atherosclerosis prediction model.
GEO web address: http://www.ncbi.nlm.nih.gov/geo/

ISSN: 1755-8794