LINE-1 methylation status and its association with tetralogy of fallot in infants

BMC Medical Genomics

Table 3 Association between LINE-1 methylation levels and risk of TOF

LINE-1 methylation level	TOF (%)	Control (%)	OR (95% CI)	P
LINE-1 methylation level	(n = 32)	(n = 15)	OR (95% CI)	P
Highest quartile (>75%)	2 (6.3)	4 (26.7)	1.0 (reference)
Medium quartile (25%–75%)	8 (25.0)	8 (53.3)	2.0 (0.3–14.2)	0.65
Lowest quartile (<25%)	22 (68.7)	3 (20.0)	14.7 (1.8–117.7)	0.014

OR, odds ratio; P, percentile; Cutoffs defined as 25% P and 75% P of the control group methylation level.

ISSN: 1755-8794