Table 3 Study population and biologic samples 1
From: Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokers
Parameter | Healthy nonsmokers | Healthy smokers |
|---|---|---|
n | 60 | 72 |
Gender (male/female) | 38/22 | 51/21 |
Age | 41 ± 12 | 43 ± 8 |
Race (B/W/O)2 | 27/23/10 | 45/16/11 |
Smoking history (pack-yr) | 0 | 27 ± 16 |
Urine nicotine (ng/ml) | negative | 1098 ± 1312 |
Urine cotinine (ng/ml) | negative | 1228 ± 939 |
Pulmonary function parameters4 | ||
FVC (% predicted) | 106 ± 13 | 110 ± 14 |
FEV1 (% predicted) | 106 ± 14 | 110 ± 15 |
FEV1/FVC (% observed) | 82 ± 6 | 81 ± 4 |
TLC (% predicted) | 99 ± 13 | 100 ± 12 |
DLCO (% predicted) | 98 ± 14 | 94 ± 11 |
Epithelial cells4 | ||
Number recovered x106 | 6.5 ± 2.9 | 7.4 ± 3.3 |
% epithelial cells5 | 99.1 ± 1.2 | 99.0 ± 1.3 |
% inflammatory cells | 0.9 ± 1.2 | 1.0 ± 1.3 |
Differential cell count6 | ||
Ciliated (%) | 72.0 ± 8.9 | 64.0 ± 12 |
Secretory (%) | 6.7 ± 3.7 | 8.4 ± 4.4 |
Basal (%) | 12.6 ± 6.6 | 14.5 ± 8.0 |
Intermediate (%) | 7.8 ± 3.4 | 12.2 ± 6.8 |