Figure 1
From: Relation between smoking history and gene expression profiles in lung adenocarcinomas
Molecular profiling identifies two subgroups of lung adenocarcinoma with differences in smoker status. Unsupervised analysis of 39 AC cases identifies two AC groups, where one (AC1) comprises all never-smoker cases. Hierarchical clustering was performed on 706 Illumina probes with log2ratio SD >1 across the 39 cases using Pearson correlation and complete linkage. The color-coded beadchip annotation bar indicates which of the seven beadchips that a specific sample was hybridized to. Approximately Unbiased (AU) p-values (%) provided by pvclust [35] analysis using 1000 bootstraps are indicated for certain branches of the hierarchical tree, where values close to 100% indicate that clusters are highly supported by data.