Skip to main content

Table 3 GO categories overrepresented in the gene set DEG_wBC (time point 0 hours) top-ranked with b) or without BC a)

From: Batch correction of microarray data substantially improves the identification of genes differentially expressed in Rheumatoid Arthritis and Osteoarthritis

TermID Members (DEG/all) P-value Category
a)
GO:0005201 3/74 5.87e-03 extracellular matrix structural constituent
GO:0050840 2/26 6.62e-03 extracellular matrix binding
GO:0005100 2/28 7.65e-02 Rho GTPase activator activity
GO:0008307 2/40 1.52e-02 structural constituent of muscle
GO:0005178 2/57 2.96e-02 integrin binding
GO:0001871 3/154 3.61e-02 pattern binding
GO:0030246 3/156 3.70e-02 carbohydrate binding
b)
GO:0005201 8/74 7.60E-07 extracellular matrix structural constituent
GO:0048407 4/11 3.29E-06 platelet-derived growth factor binding
GO:0005540 3/19 9.04E-04 hyaluronic acid binding
GO:0015355 2/5 1.02E-03 secondary active monocarboxylate transmembrane transporter activity
GO:0004035 2/6 1.52E-03 alkaline phosphatase activity
GO:0005178 4/57 2.74E-03 integrin binding
GO:0004000 2/9 3.58E-03 adenosine deaminase activity
GO:0050840 2/26 7.46E-03 extracellular matrix binding
GO:0008307 3/40 7.88E-03 structural constituent of muscle
GO:0046332 3/42 9.02E-03 SMAD binding
GO:0030674 3/44 1.02E-02 protein binding
GO:0016853 4/83 1.02E-02 isomerase activity
GO:0000287 10/441 1.53E-02 magnesium ion binding
GO:0005507 3/62 2.56E-02 copper ion binding
GO:0042802 7/289 3.17E-02 identical protein binding
GO:0005100 2/28 3.31E-02 Rho GTPase activator activity
GO:0005518 2/31 3.94E-02 collagen binding
GO:0016903 2/33 4.47E-02 oxidoreductase activity
  1. GO categories overrepresented in both data sets are highlighted in bold. Please note that both the number of the category members and the p-values for differential expression considerably improve by BC.