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Table 6 Classification of the significantly modulated genes according to their involvement in cell functions or pathways
| Ontology category | Number of genes | P-value | Gene lists |
|---|---|---|---|
| Cell Death | 12 | 3.47E-05 - 4.53E-02 | METAP2 (includes EG:10988), BACE1, ACE, CHFR, MIF, ATP1A2, SERPINB2, CLN3, RUNX1, GMFG, XRCC6, CTSD |
| Protein Synthesis | 11 | 1.77E-05 - 4.53E-02 | TRNY, METAP2 (includes EG:10988), TRNN, ACE, BACE1, CHFR, MIF, CLN3, TRND, UBE2G1, CTSD |
| Cellular Growth and Proliferation | 9 | 1.06E-03 - 4.53E-02 | PIP4K2B, METAP2 (includes EG:10988), CHFR, MIF, CLN3, SERPINB2, RUNX1, CTSD, XRCC6 |
| Lipid Metabolism | 9 | 2.41E-03 - 4.53E-02 | PIP4K2B, DHRS4, ALDH8A1, CYGB, ACE, MIF, CLN3, RUNX1, PLCB2 |
| Molecular Transport | 8 | 5.13E-03 - 4.53E-02 | ALDH8A1, ACE, MIF, CLN3, ATP1A2, RUNX1, PLCB2, CKM |
| Cellular Assembly and Organization | 7 | 2.57E-03 - 4.53E-02 | METAP2 (includes EG:10988), ACE, BACE1, CLN3, CKM, XRCC6, CTSD |
| Protein Degradation | 6 | 1.31E-04 - 5.4E-03 | ACE, BACE1, CHFR, CLN3, UBE2G1, CTSD |
| Cardiovascular System Development and Function | 5 | 1.43E-03 - 4.56E-02 | METAP2 (includes EG:10988), ACE, MIF, ATP1A2, RUNX1 |
| DNA Replication, Recombination, and Repair | 5 | 7.69E-03 - 4.78E-02 | METAP2 (includes EG:10988), CHFR, MIF, ATP1A2, XRCC6 |
| Hematological System Development and Function | 4 | 1.06E-03 - 4.04E-02 | ACE, MIF, SERPINB2, RUNX1 |
| Cell-To-Cell Signaling and Interaction | 4 | 1.3E-03 - 4.53E-02 | METAP2 (includes EG:10988), ACE, MIF, ZP2 |
| Cell Cycle | 4 | 2.57E-03 - 4.78E-02 | METAP2 (includes EG:10988), CHFR, MIF, RUNX1 |
| Cell Signaling | 2 | 1.28E-02 - 2.29E-02 | PLCB2, CKM |
