Stage | Down-regulated miRNAs | Up-regulated miRNAs |
---|---|---|
I-II | hsa-miR-449a, hsa-miR-34c-3p, hsa-miR-32, hsa-miR-34b, hsa-miR-625, hsa-miR-34b* hsa-miR-34c-5p | hsa-miR-455-5p, hsa-miR-199b-5p, hsa-miR-409-3p, hsa-miR-411, hsa-miR-107 |
III | hsa-miR-34b, hsa-miR-34c-3p, hsa-miR-34b*, hsa-miR-449a, hsa-miR-34c-5p | hsa-miR-17-5p:9.1, hsa-miR-107, hsa-miR-409-3p, hsa-miR-18a, hsa-miR-339-5p, hsa-miR-99a, hsa-miR-34a*, hsa-miR-411, hsa-miR-455-5p, hsa-miR-149 |
IV | hsa-miR-32, hsa-miR-449a, | hsa-miR-99a, hsa-miR-199b-5p, hsa-miR-99b, hsa-miR-339-5p, hsa-miR-708, hsa-miR-200a*, hsa-miR-18b, hsa-miR-20a*, hsa-miR-409-3p, hsa-miR-107, hsa-miR-18a*, hsa-miR-17-5p:9.1, hsa-miR-34a*, hsa-miR-503, hsa-miR-455-5p, hsa-miR-411, hsa-miR-18a, hsa-miR-149 |
Metastasis | hsa-miR-449a, hsa-miR-32, hsa-miR-34b*, hsa-miR-34c-5p, hsa-miR-186, hsa-miR-130b, hsa-miR-34c-3p, hsa-miR-34b, hsa-miR-181c, hsa-miR-361-3p, hsa-miR-429, hsa-miR-625, hsa-miR-335, hsa-let-7c, hsa-miR-29c, hsa-miR-421, hsa-miR-141, hsa-miR-29a | hsa-miR-708, hsa-miR-149, hsa-miR-20a*, hsa-miR-34a*, hsa-miR-99a, hsa-miR-107, hsa-let-7d*, hsa-miR-483-3p, hsa-miR-18b, hsa-miR-455-5p, hsa-miR-199b-5p, hsa-miR-193a-5p, hsa-miR-99b, hsa-miR-503, hsa-miR-18a, hsa-miR-409-3p, hsa-miR-411, hsa-miR-1, hsa-miR-206 |