TY - JOUR AU - Trakadis, Yannis J. PY - 2012 DA - 2012/07/20 TI - Patient-controlled encrypted genomic data: an approach to advance clinical genomics JO - BMC Medical Genomics SP - 31 VL - 5 IS - 1 AB - The revolution in DNA sequencing technologies over the past decade has made it feasible to sequence an individual’s whole genome at a relatively low cost. The potential value of the information generated by genomic technologies for medicine and society is enormous. However, in order for exome sequencing, and eventually whole genome sequencing, to be implemented clinically, a number of major challenges need to be overcome. For instance, obtaining meaningful informed-consent, managing incidental findings and the great volume of data generated (including multiple findings with uncertain clinical significance), re-interpreting the genomic data and providing additional counselling to patients as genetic knowledge evolves are issues that need to be addressed. It appears that medical genetics is shifting from the present “phenotype-first” medical model to a “data-first” model which leads to multiple complexities. SN - 1755-8794 UR - https://doi.org/10.1186/1755-8794-5-31 DO - 10.1186/1755-8794-5-31 ID - Trakadis2012 ER -