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Table 3 SNPs significantly associated with SMX-induced hypersensitivity (uncorrected p values)

From: Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients

Marker

Gene

MAF

P value

rs761142

GCLC

0.32

0.0006

rs2179625

CAT

0.21

0.0027

rs1736557

FMO3

0.06

0.0034

rs6933870

GCLC

0.46

0.0097

rs554576

CAT

0.46

0.013

rs2236271

GSS

0.32

0.016

rs10306135

PTGS1

0.15

0.018

rs6060127

GSS

0.28

0.018

rs7104301

CAT

0.23

0.020

rs3736729

GCLC

0.50

0.028

rs10488736

CAT

0.33

0.034

rs4958873

GPX3

0.38

0.035

rs670548

GCLC

0.25

0.065