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Table 4 Association between SNP rs761142 in GCLC and SMX-induced hypersensitivity

From: Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients

Genotype

Count (%)

 

Odds ratio (95% CL)

P value

 

With hypersensitivity

Without hypersensitivity

  

TT

31 (30%)

164 (52%)

1

 

TG

54 (53%)

127 (40%)

2.2 (1.4 – 3.7)

0.0014

GG

17 (17%)

27 (8%)

3.3 (1.6 – 6.8)

0.0010

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