Figure 1

Predicted miR-7 and miR-128 target sites (miRanda) on EGFR (epidermal growth factor receptor gene) 3’UTR (untranslated region). (A) Nucleotide sequences of miR-128 and miR-7 “seed” regions and complementary “target” sequences on the EGFR UTR. Vertical lines ( | ) denote Watson-Crick base pairing, while the colon (:) sign denotes wobble between G and U on opposite strands. (B) Schematic illustration of the relative location of each target site on the EGFR gene.