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Table 1 Fraction of down-regulated, up-regulated and total differentially expressed genes predicted to be targets of miRNAs

From: The effects of MicroRNA transfections on global patterns of gene expression in ovarian cancer cells are functionally coordinated

  miR-7 miR-128
  M TS PT AVG M TS PT AVG
Down (%) 32.4 10.2 6.5 16.4 36.0 14.7 9.1 19.9
Up (%) 12.3 1.9 0.6 4.9 18.8 3.8 2.6 8.4
All (%) 28.2 8.5 5.3 14.0 24.0 7.1 4.6 11.9
  1. Significantly down-regulated (Down), up-regulated (Up) or total differentially expressed genes (All) after miR-7 or miR-128 transfections in HEY cells were searched for targets of the respective miRNAs using miRanda (M), TargetScan (TS) and PicTar (PT) algorithms. The fraction (%) of targets within each group and the average (AVG) of all 3 algorithms are reported in this table.