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Table 1 Fraction of down-regulated, up-regulated and total differentially expressed genes predicted to be targets of miRNAs

From: The effects of MicroRNA transfections on global patterns of gene expression in ovarian cancer cells are functionally coordinated

 

miR-7

miR-128

 

M

TS

PT

AVG

M

TS

PT

AVG

Down (%)

32.4

10.2

6.5

16.4

36.0

14.7

9.1

19.9

Up (%)

12.3

1.9

0.6

4.9

18.8

3.8

2.6

8.4

All (%)

28.2

8.5

5.3

14.0

24.0

7.1

4.6

11.9

  1. Significantly down-regulated (Down), up-regulated (Up) or total differentially expressed genes (All) after miR-7 or miR-128 transfections in HEY cells were searched for targets of the respective miRNAs using miRanda (M), TargetScan (TS) and PicTar (PT) algorithms. The fraction (%) of targets within each group and the average (AVG) of all 3 algorithms are reported in this table.