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Table 1 Heritability of the inhibitory concentration of experimental drugs

From: Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines

Threshold (%)

Imatinib

Omacetaxine

 

Mean dose (x10-5M)

h2

P

Mean dose (x10-8M)

h2

p

10

1.48

0.60

5.76x10-4

1.04

0.00

0.50

20

3.32

0.60

5.81x10-4

2.35

0.00

0.50

30

5.70

0.60

5.81x10-4

4.03

0.00

0.50

40

8.86

0.60

5.81x104

6.27

0.00

0.50

50

13.29

0.60

5.73x10-4

9.40

0.00

0.50

60

19.03

0.73

1.92x10-5

14.10

0.00

0.50

70

31.00

0.60

5.73x10-4

21.93

0.00

0.50

80

53.14

0.60

5.81x10-4

37.59

0.00

0.50

90

119.60

0.60

5.74x10-4

84.58

0.00

0.50

  1. h2, heritability.