Table 2 Concordance of functional annotation cluster (using DAVID®) with the four clusters identified based on differential gene expression

Number of genes

Total

1378

2005

428

642

Identified as human by DAVID

1332

1932

416

617

Mapped by DAVID with GO terms

1187 (86.1%)

1704 (85.0%)

380 (88.8%)

532 (82.9%)

Functional cluster rank (enrichment score*)

1

Mitochondria

Mitosis

Vacuole

Anti-apoptosis

(12.08)

(24.40)

(10.18)

(2.72)

2

Ribosomes

Kinetochore

Endocytosis

Kinase binding

(7.72)

(16.34)

(2.82)

(2.67)

3

Catabolism

Intracellular organelle

Cell fraction

Apoptosis regulation

(6.53)

(12.53)

(2.56)

(2.59)

4

Intracellular organelle

DNA Replication

Metal ion binding

Intracellular organelle

(4.80)

(11.96)

(2.37)

(2.25)

5

Ubiquitination

DNA Repair

Lysosome

Metal ion binding

(4.10)

(11.85)

(1.86)

(2.05) and

Tyrosine kinase activity

(2.05)