Table 3 Annotation of the 34 genes that were differentially expressed upon treatment as well as associated with SDR
Probe ID | Gene symbol | Gene name | Cluster | iFC | oFC | Pathways |
|---|---|---|---|---|---|---|
ILMN_1691364 | STAT1 | Signal transducer and activator of transcription 1, 91 kDa | 1 | −0.1071 | 0.2270 | IFNα/ß/Γ; oncostatin M, Thrombopoetin; Angiopoetin, PDGF; IL-1/IL-9/IL-22;/IL23; EGFR; p53; SUMO-1; Leptin |
ILMN_1700028 | C9orf156 | Chromosome 9 open reading frame 156 | 1 | −0.0526 | 0.2686 | |
ILMN_1747771 | MAEA | Macrophage erythroblast attacher | 1 | −0.0370 | 0.2202 | |
ILMN_1751803 | LSM10 | LSM10, U7 small nuclear RNA associated | 1 | −0.0924 | 0.1841 | |
ILMN_1770892 | YY1 | YY1 transcription factor | 1 | 0.0556 | 0.2401 | TGF-ß signaling, NOTCH signaling, p53 signaling |
ILMN_2258268 | GLRX2 | Glutaredoxin 2 | 1 | −0.1088 | 0.2979 | |
ILMN_2309228 | GPS1 | G protein pathway suppressor 1 | 1 | 0.0364 | 0.3378 | |
ILMN_1659753 | LAMP2 | Lysosomal-associated membrane protein 2 | 2 | 0.0400 | −0.2695 | |
ILMN_1677691 | GP2 | Glycoprotein 2 (zymogen granule membrane) | 2 | 0.0012 | −0.3267 | Integrin inside-out signaling |
ILMN_1682775 | EDN1 | Endothelin 1 | 2 | −0.5040 | −0.4670 | Leptin signaling via JAK/STAT & MAPK, EGFR transactivation, IL-1 signaling, EDRNA signaling |
ILMN_1695058 | SLC38A5 | Solute carrier family 38, member 5 | 2 | −0.1257 | −0.2268 | |
ILMN_1703906 | HJURP | Holliday junction recognition protein | 2 | −0.0682 | −0.6162 | |
ILMN_1707591 | TNIP3 | TNFAIP3 interacting protein 3 | 2 | −0.3585 | −0.5433 | |
ILMN_1713952 | C1orf106 | Chromosome 1 open reading frame 106 | 2 | −0.0368 | −0.3012 | |
ILMN_1732516 | KNTC1 | Kinetochore associated 1 | 2 | −0.0216 | −0.3534 | Spindle assembly |
ILMN_1769545 | PRPF19 | PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) | 2 | −0.0770 | −0.3237 | NOTCH signaling |
ILMN_1774077 | GBP2 | Guanylate binding protein 2, interferon-inducible | 2 | −0.0388 | −0.4636 | |
ILMN_1849494 | EFR3B | EFR3 homolog B (S. cerevisiae) | 2 | −0.0256 | −0.4698 | |
ILMN_1868655 | AI916641 | 2 | −0.1451 | −0.4635 | ||
ILMN_1898692 | BI254341 | 2 | −0.2912 | −0.3491 | ||
ILMN_1912827 | CB157495 | 2 | −0.1382 | −0.5097 | ||
ILMN_2103685 | DEPDC1B | DEP domain containing 1B | 2 | −0.1807 | −0.7007 | |
ILMN_2230162 | FLJ44124 | Hypothetical LOC641737 | 2 | 0.0233 | −0.3135 | |
ILMN_2336595 | ACSS2 | Acyl-CoA synthetase short-chain family member 2 | 2 | 0.1570 | −0.5157 | |
ILMN_2384544 | ADAM15 | ADAM metallopeptidase domain 15 | 2 | 0.2186 | −0.3365 | |
ILMN_1677200 | CYFIP2 | Cytoplasmic FMR1 interacting protein 2 | 3 | 0.3287 | −0.2998 | G-protein signaling RAC1 |
ILMN_1724437 | GCAT | Glycine C-acetyltransferase (2-amino-3- ketobutyrate coenzyme A ligase) | 3 | 0.2763 | −0.1991 | |
ILMN_1789436 | AK091207 | 3 | 0.4950 | 0.2848 | ||
ILMN_2392352 | CTPS2 | CTP synthase II | 3 | 0.1718 | 0.0349 | |
ILMN_1664798 | GRHPR | Glyoxylate reductase/hydroxypyruvate reductase | 4 | 0.1026 | 0.4346 | |
ILMN_1693338 | CYP1B1 | Cytochrome P450, family 1, subfamily B, polypeptide 1 | 4 | 0.1427 | 0.4242 | Benzopyrene, estradiol and retinol metabolism |
ILMN_1764361 | DUSP16 | Dual specificity phosphatase 16 | 4 | 0.2176 | 0.6187 | p53; Erk |
ILMN_1779428 | C12orf68 | Chromosome 12 open reading frame 68 | 4 | 0.0770 | 0.3965 | |
ILMN_1794956 | BBS9 | Bardet-Biedl syndrome 9 | 4 | 0.1743 | 0.5875 |