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Table 3 Annotation of the 34 genes that were differentially expressed upon treatment as well as associated with SDR

From: Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines

Probe ID Gene symbol Gene name Cluster iFC oFC Pathways
ILMN_1691364 STAT1 Signal transducer and activator of transcription 1, 91 kDa 1 −0.1071 0.2270 IFNα/ß/Γ; oncostatin M, Thrombopoetin; Angiopoetin, PDGF; IL-1/IL-9/IL-22;/IL23; EGFR; p53; SUMO-1; Leptin
ILMN_1700028 C9orf156 Chromosome 9 open reading frame 156 1 −0.0526 0.2686  
ILMN_1747771 MAEA Macrophage erythroblast attacher 1 −0.0370 0.2202  
ILMN_1751803 LSM10 LSM10, U7 small nuclear RNA associated 1 −0.0924 0.1841  
ILMN_1770892 YY1 YY1 transcription factor 1 0.0556 0.2401 TGF-ß signaling, NOTCH signaling, p53 signaling
ILMN_2258268 GLRX2 Glutaredoxin 2 1 −0.1088 0.2979  
ILMN_2309228 GPS1 G protein pathway suppressor 1 1 0.0364 0.3378  
ILMN_1659753 LAMP2 Lysosomal-associated membrane protein 2 2 0.0400 −0.2695  
ILMN_1677691 GP2 Glycoprotein 2 (zymogen granule membrane) 2 0.0012 −0.3267 Integrin inside-out signaling
ILMN_1682775 EDN1 Endothelin 1 2 −0.5040 −0.4670 Leptin signaling via JAK/STAT & MAPK, EGFR transactivation, IL-1 signaling, EDRNA signaling
ILMN_1695058 SLC38A5 Solute carrier family 38, member 5 2 −0.1257 −0.2268  
ILMN_1703906 HJURP Holliday junction recognition protein 2 −0.0682 −0.6162  
ILMN_1707591 TNIP3 TNFAIP3 interacting protein 3 2 −0.3585 −0.5433  
ILMN_1713952 C1orf106 Chromosome 1 open reading frame 106 2 −0.0368 −0.3012  
ILMN_1732516 KNTC1 Kinetochore associated 1 2 −0.0216 −0.3534 Spindle assembly
ILMN_1769545 PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) 2 −0.0770 −0.3237 NOTCH signaling
ILMN_1774077 GBP2 Guanylate binding protein 2, interferon-inducible 2 −0.0388 −0.4636  
ILMN_1849494 EFR3B EFR3 homolog B (S. cerevisiae) 2 −0.0256 −0.4698  
ILMN_1868655 AI916641   2 −0.1451 −0.4635  
ILMN_1898692 BI254341   2 −0.2912 −0.3491  
ILMN_1912827 CB157495   2 −0.1382 −0.5097  
ILMN_2103685 DEPDC1B DEP domain containing 1B 2 −0.1807 −0.7007  
ILMN_2230162 FLJ44124 Hypothetical LOC641737 2 0.0233 −0.3135  
ILMN_2336595 ACSS2 Acyl-CoA synthetase short-chain family member 2 2 0.1570 −0.5157  
ILMN_2384544 ADAM15 ADAM metallopeptidase domain 15 2 0.2186 −0.3365  
ILMN_1677200 CYFIP2 Cytoplasmic FMR1 interacting protein 2 3 0.3287 −0.2998 G-protein signaling RAC1
ILMN_1724437 GCAT Glycine C-acetyltransferase (2-amino-3- ketobutyrate coenzyme A ligase) 3 0.2763 −0.1991  
ILMN_1789436 AK091207   3 0.4950 0.2848  
ILMN_2392352 CTPS2 CTP synthase II 3 0.1718 0.0349  
ILMN_1664798 GRHPR Glyoxylate reductase/hydroxypyruvate reductase 4 0.1026 0.4346  
ILMN_1693338 CYP1B1 Cytochrome P450, family 1, subfamily B, polypeptide 1 4 0.1427 0.4242 Benzopyrene, estradiol and retinol metabolism
ILMN_1764361 DUSP16 Dual specificity phosphatase 16 4 0.2176 0.6187 p53; Erk
ILMN_1779428 C12orf68 Chromosome 12 open reading frame 68 4 0.0770 0.3965  
ILMN_1794956 BBS9 Bardet-Biedl syndrome 9 4 0.1743 0.5875  
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