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Table 1 Characteristic of patients and datasets

From: Immune genes are associated with human glioblastoma pathology and patient survival

Name Dataset origin de Tayrac GSE4271 GSE4412 Lee GSE13041 Verhaak TCGA Data Portal Petalidis GSE2727 Local_1 CHU Rennes CHU Angers Local_2 CHU Rennes
Technology Number of samples Affymetrix Affymetrix Affymetrix Affymetrix Agilent Q-PCR
   115 161 173 39 41 57
Gender Male M:65 M:96 M:112 M:29 M:21 M:31
Female F:50 F:65 F:61 F:10 F:20 F:26
Age (y) median [min-max] 48 [18-82] 55 [22-86] 59 [14-87] 61 [22-74] 58 [33-80] 59 [36-78]
<50 65 59 56 14 10 10
> = 50 50 102 117 25 31 47
KPS (%) median - - 90 [40-100] - 80 [40-100] 80 [40-100]
<=70 - - 22 - 15 28
>70 - - 58 - 23 29
NA - -   - 3 -
Treatment (surgical) biopsy - - 6   1 2
partial resection - - -   8 17
total resection - 161(a) 164 (c) 26 38
NA - - 1   6 -
Treatment (adjuvant) RT -     3 -
RT + CT like Stupp’s schedule - (b) (b) (c) 37 57
no treatment -     1 -
MGMT status Methylated - 86 42 - 24 27
Un-methylated - 75 122 - 17 29
NA - - - - - 1
IDH1 status Wild-type - - 167 - 39 39
Mutated - - 6 - 2 1
NA - - - - - 17
Subtype Proneural - 41 48 - 12 -
  non-Proneural - 120 125 - 29 -
  1. (a) ‘resection mentioned alone with no other details.
  2. (b) Excessively heterogeneous treatment. GBM de novo tumors with no prior treatment.
  3. (c) Data not available.