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Table 4 Single gene scores and proliferation across PAM50 subtypes

From: PAM50 Breast Cancer Subtyping by RT-qPCR and Concordance with Standard Clinical Molecular Markers

  Proliferation ESR1^ PGR^ ERBB2^
LumA Low-104 (38%) Neg-0 (0%) Neg-15 (5%) Neg-254 (92%)
n = 277 Intermediate-116 (42%) Pos-277 (100%) Pos-262 (95%) Pos-23 (8%)
  High-57 (11%)    
LumB Low-4 (2%) Neg-8 (3%) Neg-101 (39%) Neg-194 (74%)
n = 261 Intermediate-55 (21%) Pos-253 (97%) Pos-160 (61%) Pos-67 (26%)
  High-202 (77%)    
HER2-E Low-15 (9%) Neg-76 (44%) Neg-112 (64%) Neg-81 (47%)
n = 174 Intermediate-60 (34%) Pos-98 (56%) Pos-62 (36%) Pos-93 (53%)
  High-99 (57%)    
Basal Low-0 (0%) Neg-67 (96%) Neg-67 (96%) Neg-66 (94%)
n = 70 Intermediate-3 (4%) Pos-3 (4%) Pos-3 (4%) Pos-4 (6%)
  High-67 (96%)    
  1. ^ RT-qPCR status based on intermediate-high (positive) versus low (negative).