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Table 1 Over-represented canonical pathways in genes that correlated with CPRS-R for IA, HI or both

From: Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in tourette syndrome: a pilot study

Canonical pathways

P-value

Canonical pathways associated with common IA-HI genes

IL-4 Signaling

1.10 x 10-4

B Cell Receptor Signaling

1.30 x 10-4

Axonal Guidance Signaling

9.43 x 10-4

T Cell Receptor Signaling

4.95 x 10-3

Glucocorticoid Receptor Signaling

8.09 x 10-3

Canonical pathways associated with HI-specific genes

Integrin Signaling

7.29 x 10-6

Toll-like Receptor Signaling

1.61 x 10-4

B Cell Receptor Signaling

1.77 x 10-4

Role of NFAT in Regulation of the Immune Response

2.71 x 10-4

Growth Hormone Signaling

4.71 x 10-4

Natural Killer Cell Signaling

8.54 x 10-4

Canonical pathways associated with IA-specific genes

B Cell Development

2.74 x 10-5

Antigen Presentation Pathway

4.93 x 10-3

Cardiac β-adrenergic Signaling

7.88 x 10-3

B Cell Receptor Signaling

1.02 x 10-2

Primary Immunodeficiency Signaling

1.40 x 10-2

GM-CSF Signaling

2.15 x 10-2