Cell Line Derived Multi-Gene Predictor of Pathologic Response to Neoadjuvant Chemotherapy in Breast Cancer: A Validation Study on US Oncology 02-103 Clinical Trial

Table 3 Univariate and multivariate analysis results for FEC/TX plus H group (n=25)

	Univariate logistic regression analysis		Multivariate logistic regression analysis
	OR (95% CI)	p-value	OR (95% CI)	p-value
Age	0.99 (0.88, 1.10)	0.83	0. 91 (0.68, 1.22)	0.53
ER	0.13 (0.02, 0.82)	0.03	0.01 (0.00, 2.21)	0.09
Nodal	2.25 (0.32, 15.76)	0.41	0.15 (0.00, 7.94)	0.26
T	1.53 (0.5, 4.63)	0.45	0.66(0.07, 6.68)	0.73
Grade	0.22 (0.04, 1.37)	0.11	0.05 (0 .00, 2.33)	0.13
MGP scores	11.93 (0.00, 1.27E+06)	0.67	1.85E+06 (0.00, 1.35E+16)	0.21

OR: odds ratio for having pCR vs. RD; CI, confidence interval; p-value. The comparison vs. reference state for the categorical variables were ER, estrogen receptor (positive vs. negative) Nodal (positive vs. negative); T (Tumor size); Grade (grade 3 vs. 2) and MGP scores.

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