Table 3 Allele frequencies in COPD and control subjects for SNPs

rs1059823

G

139(33)

222(34)

0.0181

0.8929

1.01

0.79-1.32

67.8604

0.8290

0.97

0.74-1.27

63.0040

A

283(67)

440(66)

rs1205

C

168(40)

308(47)

5.2168

0.0223

1.34

1.04-1.71

1.6948

0.0030

1.48

1.14-1.91

0.2280

T

252(60)

346(53)

rs17019336

A

136(32)

242(37)

2.1770

0.1401

1.21

0.94-1.57

10.6476

0.0670

1.28

0.98-1.68

5.0920

T

284(68)

416(63)

rs1799964

T

333(79)

519(79)

0.0008

0.9772

1.00

0.74-1.36

74.2672

0.8140

0.96

0.71-1.31

61.8640

C

87(21)

135(21)

rs1800610

T

71(17)

112(17)

0.0117

0.9137

1.02

0.74-1.41

69.4412

0.9007

0.98

0.70-1.38

68.4532

C

355(83)

550(83)

rs2077464

T

271(65)

420(66)

0.1909

0.6621

1.06

0.82-1.37

50.3196

0.8230

1.03

0.79-1.35

62.5480

C

149(35)

218(34)

rs2236302

C

369(88)

584(89)

0.2011

0.6539

1.09

0.75-1.59

49.6964

0.4140

1.18

0.80-1.75

31.4640

G

51(12)

74(11)

rs2292566

A

125(30)

209(32)

0.4800

0.4884

1.10

0.84-1.43

37.1184

0.7630

1.04

0.79-1.38

57.9880

G

295(70)

449(68)

rs2353397

C

123(29)

382(58)

83.3798

6.8×10 ^-20

3.29

2.54-4.28

5.2×10 ^-18

<0.0001

2.16

1.66-2.81

<0.0001

T

297(71)

280(42)

rs25882

T

147(35)

240(36)

0.2421

0.6227

1.07

0.83-1.38

47.3252

0.4650

1.10

0.85-1.44

35.3400

C

273(65)

418(64)

rs2808630

C

66(16)

119(18)

1.0136

0.3140

1.18

0.85-1.65

23.8640

0.2120

0.86

0.69-1.09

16.1120

T

354(84)

539(82)

rs3749893

A

286(67)

454(69)

0.6232

0.4299

1.11

0.86-1.44

32.6724

0.4510

1.11

0.84-1.46

34.2760

G

140(33)

200(31)

rs4987835

A

236(56)

382(60)

1.7185

0.1899

1.19

0.92-1.51

14.4324

0.2950

1.15

0.88-1.49

22.4200

G

184(44)

252(40)

rs709932

A

73(17)

131(20)

1.2714

0.2595

1.20

0.87-1.65

19.7220

0.2860

1.19

0.86-1.65

21.7360

G

347(83)

519(80)

rs7217852

A

273(65)

434(66)

0.0652

0.7985

1.03

0.80-1.34

60.6860

0.8460

1.03

0.79-1.34

64.2960

G

147(35)

226(34)

rs7776375

A

270(63)

438(66)

0.8832

0.3473

1.13

0.88-1.46

26.3948

0.2570

1.17

0.89-1.52

19.5320

G

156(37)

224(34)

rs10069690

C

331(80)

520(81)

0.0264

0.8709

1.03

0.75-1.40

66.1884

0.6480

1.08

0.78-1.48

49.2480

T

81(20)

124(19)

rs1051740

T

247(60)

403(61)

0.0424

0.8369

1.03

0.79-1.32

63.6044

0.8910

1.02

0.79-1.32

67.7160

C

163(40)

259(39)

rs11155242

A

372(90)

604(91)

0.5784

0.4469

1.18

0.77-1.79

33.9644

0.2560

1.28

0.83-1.94

19.4560

C

42(10)

58(9)

rs1295685

T

118(29)

221(33)

2.8124

0.0935

1.26

0.96-1.64

7.1060

0.1730

1.21

0.92-1.60

13.1480

C

296(71)

441(67)

rs1435867

C

55(13)

90(14)

0.0200

0.8877

1.03

0.72-1.47

67.4652

0.5300

0.89

0.62-1.29

40.5080

T

355(87)

566(86)

rs16909898

G

33(8)

54(8)

0.0101

0.9200

1.02

0.65-1.61

69.9200

0.3140

0.79

0.50-1.25

23.8640

A

379(92)

606(92)

rs1881457

A

308(74)

495(75)

0.0726

0.7876

1.04

0.78-1.38

59.8576

0.9120

1.02

0.76-1.36

69.3120

C

108(26)

167(25)

rs2241718

T

114(28)

206(31)

1.4433

0.2296

1.18

0.90-1.55

17.4496

0.2930

1.16

0.88-1.53

22.2680

C

298(72)

456(69)

rs2277027

C

64(15)

106(16)

0.0586

0.8088

1.04

0.74-1.46

61.4688

0.8350

0.96

0.68-1.36

63.4600

A

350(85)

556(84)

rs2736100

T

231(57)

368(58)

0.1539

0.6948

1.05

0.82-1.35

52.8048

0.6340

1.06

0.82-1.38

48.1840

G

173(43)

262(42)

rs35621

C

305(74)

499(75)

0.1317

0.7167

1.05

0.79-1.40

54.4692

0.3480

1.15

0.86-1.54

26.4480

T

105(26)

163(25)

rs3995090

C

288(70)

461(71)

0.1521

0.6965

1.06

0.80-1.39

52.9340

0.4200

1.12

0.84-1.48

31.9200

A

122(30)

185(29)

rs4246742

A

244(60)

429(65)

3.0339

0.0815

1.25

0.97-1.61

6.1940

0.0510

1.32

1.01-1.71

3.8760

T

166(40)

233(35)

rs6712954

G

321(78)

545(82)

3.1679

0.0751

1.32

0.97-1.79

5.7076

0.0560

1.38

1.01-1.89

4.2560

A

91(22)

117(18)

rs829259

A

137(33)

233(35)

0.4250

0.5145

1.09

0.84-1.41

39.1020

0.9300

1.01

0.77-1.32

70.6800

T

275(67)

429(65)

rs10075508

T

69(16)

108(17)

0.0253

0.8736

1.03

0.74-1.43

66.3936

0.9070

1.02

0.72-1.44

68.9320

C

357(84)

544(83)

rs10512249

T

33(8)

52(8)

0.0606

0.8056

1.06

0.67-1.67

61.2256

0.4950

1.16

0.75-1.80

37.6200

C

383(92)

570(92)

rs12899618

G

370(89)

579(89)

0.0806

0.7765

1.06

0.72-1.56

59.0140

0.6010

1.11

0.75-1.65

45.6760

A

48(11)

71(11)

rs13706

G

272(65)

427(65)

0.0598

0.8068

1.03

0.80-1.34

61.3168

0.8300

0.97

0.75-1.27

63.0800

A

148(35)

225(35)

rs1531697

A

255(61)

411(63)

0.5370

0.4637

1.10

0.85-1.41

35.2412

0.4750

1.10

0.85-1.43

36.1000

T

163(39)

239(37)

rs1800925

T

62(15)

105(17)

0.8620

0.3531

1.18

0.84-1.66

26.8356

0.1000

1.32

0.94-1.85

7.6000

C

352(85)

507(83)

rs3024791

G

388(93)

616(95)

1.5299

0.2161

1.39

0.82-2.34

16.4236

0.3820

1.25

0.76-2.06

29.0320

A

28(7)

32(5)

rs6537302

A

310(75)

480(77)

0.7206

0.3959

1.13

0.85-1.51

30.0884

0.9110

1.10

0.76-1.36

69.2360

T

104(25)

142(23)

rs6555465

G

195(46)

310(48)

0.4399

0.5072

1.09

0.85-1.39

38.5472

0.5010

1.09

0.85-1.41

38.0760

A

231(54)

338(52)

rs673400

C

178(43)

278(43)

0.0062

0.9371

1.01

0.79-1.30

71.2196

0.9280

0.99

0.76-1.28

70.5280

G

238(57)

368(57)

rs6889822

G

268(64)

417(65)

0.0594

0.8073

1.03

0.80-1.34

61.3548

0.5000

1.10

0.84-1.43

38.0000

A

148(36)

223(35)

rs8004738

G

184(44)

275(44)

0.0092

0.9236

1.01

0.79-1.30

70.1936

0.6650

1.01

0.82-1.37

50.5400

A

232(56)

351(56)

rs1003349

G

238(57)

392(60)

0.8897

0.3456

1.13

0.88-1.45

26.2656

0.2340

1.17

0.90-1.51

17.7840

T

178(43)

260(40)

rs1032295

T

320(75)

523(80)

3.1870

0.0742

1.30

0.97-1.74

5.6392

0.1130

1.28

0.94-1.73

8.5880

G

106(25)

133(20)

rs1042522

C

184(44)

304(47)

0.8170

0.3660

1.12

0.88-1.43

27.8160

0.4090

1.11

0.86-1.44

31.0840

G

236(56)

348(53)

rs1052443

C

281(67)

457(71)

1.7602

0.1846

1.20

0.92-1.56

14.0296

0.1610

1.22

0.93-1.60

12.2360

A

139(33)

189(29)

rs12504628

T

305(72)

475(72)

0.0847

0.7710

1.04

0.79-1.37

58.5960

0.9810

1.04

0.76-1.33

74.5560

C

121(28)

181(28)

rs1695

G

72(17)

126(19)

0.6673

0.4140

1.14

0.83-1.57

31.4640

0.4650

1.13

0.82-1.57

35.3400

A

346(83)

530(81)

rs1800469

C

182(44)

315(48)

2.1252

0.1449

1.20

0.94-1.54

11.0124

0.2010

1.74

1.35-2.27

15.2760

T

234(56)

337(52)

rs20541

T

118(28)

228(35)

5.3633

0.0206

1.37

1.05-1.79

1.5656

0.0280

1.36

1.04-1.80

2.1280

C

302(72)

426(65)

rs2070600

G

312(73)

529(81)

8.1712

0.0043

1.52

1.14-2.03

0.3268

0.0130

1.47

1.08-1.98

0.9880

A

114(27)

127(19)

rs2853209

A

191(45)

305(47)

0.1953

0.6586

1.06

0.83-1.35

50.0536

0.9890

0.10

0.77-1.29

75.1640

T

231(55)

349(53)

rs4073

A

185(44)

300(46)

0.5198

0.4709

1.10

0.86-1.40

35.7884

0.2530

1.16

0.90-1.50

19.2280

T

235(56)

348(54)

rs6937121

T

254(60)

423(65)

2.1263

0.1448

1.21

0.94-1.56

11.0048

0.1720

1.20

0.92-1.56

13.0720

G

166(40)

229(35)

rs6957

G

150(36)

241(37)

0.0802

0.7771

1.04

0.80-1.34

59.0596

0.6830

1.06

0.81-1.38

51.9080

A

268(64)

415(63)

rs1051730

C

403(97)

641(97)

0.2343

0.6284

1.20

0.57-2.52

47.3252

0.6480

1.17

0.60-2.29

49.2480

T

11(3)

21(3)

rs10947233

G

299(72)

526(79)

7.4524

0.0063

1.49

1.12-1.98

0.4788

0.0060

1.51

1.12-2.03

0.4560

T

115(28)

136(21)

rs11106030

C

355(85)

560(85)

0.0013

0.9716

1.01

0.71-1.42

73.8416

0.7030

1.07

0.75-1.52

53.4280

A

63(15)

100(15)

rs1130864

T

23(6)

43(7)

0.6081

0.4355

1.23

0.73-2.07

33.0980

0.3890

1.24

0.77-2.00

29.5640

C

389(94)

591(93)

rs1800629

G

379(90)

627(95)

7.8793

0.0050

1.94

1.21-3.10

0.3800

0.0060

1.97

1.21-3.21

0.4560

A

41(10)

35(5)

rs2241712

A

188(45)

342(52)

3.9820

0.0460

1.28

1.00-1.64

3.4960

0.0498

1.24

0.96-1.59

3.7848

G

226(55)

320(48)

rs2280090

G

395(94)

629(95)

0.9844

0.3211

1.30

0.77-2.20

24.4036

0.4640

1.22

0.72-2.06

35.2640

A

27(6)

33(5)

rs2395730

A

119(28)

209(32)

1.3886

0.2386

1.17

0.90-1.54

18.1336

0.0850

1.28

0.97-1.69

6.4600

C

303(72)

453(68)

rs2736118

A

397(94)

630(95)

0.6150

0.4329

1.24

0.72-2.12

32.9004

0.2850

1.36

0.78-2.37

21.6600

G

25(6)

32(5)

rs2736122

C

388(94)

632(95)

1.5783

0.2090

1.41

0.82-2.42

15.884

0.0510

1.77

1.02-3.07

3.8760

T

26(6)

30(5)

rs3817928

A

370(89)

596(90)

0.1202

0.7288

1.07

0.72-1.61

55.3888

0.4410

1.17

0.78-1.76

33.5160

G

44(11)

66(10)

rs584367

T

91(22)

152(23)

0.1399

0.7083

1.06

0.79-1.42

53.8308

0.8590

1.03

0.76-1.39

65.2840

C

323(78)

510(77)

rs1042714

C

374(90)

607(92)

1.1947

0.2744

1.27

0.83-1.96

20.8544

0.1440

1.39

0.90-2.14

10.9440

G

40(10)

374(90)

rs13147758

A

283(69)

464(71)

0.8780

0.3487

1.14

0.87-1.49

26.5012

0.3840

1.13

0.86-1.49

29.1840

G

129(31)

186(29)

rs1422795

G

61(15)

108(16)

0.5395

0.4626

1.14

0.81-1.60

35.1576

0.8690

1.03

0.73-1.46

66.0440

A

353(85)

550(84)

rs1800796

C

293(71)

473(72)

0.1539

0.6948

1.06

0.80-1.39

52.8048

0.8250

1.03

0.78-1.36

62.7000

G

121(29)

185(28)

rs2236307

C

169(41)

286(43)

0.7270

0.3938

1.11

0.87-1.43

29.9288

0.4150

1.11

0.86-1.44

31.5400

T

245(59)

372(57)

rs2280091

A

383(93)

611(93)

0.1518

0.6968

1.10

0.68-1.77

52.9568

0.5020

1.17

0.74-1.87

38.1520

G

31(7)

45(7)

rs2853676

G

335(81)

544(83)

0.4538

0.5005

1.12

0.81-1.54

38.0380

0.2770

1.20

0.86-1.67

21.0520

A

77(19)

112(17)

rs868966

A

205(50)

337(51)

0.2934

0.5880

1.07

0.84-1.37

44.6880

0.7890

1.04

0.80-1.34

59.9640

G

209(50)

321(49)