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Table 4 Analysis of Genotypic Association of SNPs identified under Genetic Models

From: Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case–control study

SNP

Genotype model

Control (n,%)

Case (n,%)

P value*

OR*

OR(95%CI) *

rs2353397

CC+CT

104(50)

261(79)

<0.0001

1.01

0.79-1.32

 

TT

106(50)

70(21)

   

rs2070600

GG

100(47)

213(65)

0.0240

1.55

1.06-2.26

 

GA+AA

113(53)

115(35)

   

rs10947233

GG+GT

191(92)

319(96)

0.0040

3.30

1.47-7.44

 

TT

16(8)

12(4)

   

rs10947233

GG

108(52)

207(63)

0.0200

1.56

1.07-2.27

 

GT+TT

99(48)

124(37)

   

rs1800629

GG

171(81)

296(89)

0.0170

1.90

1.12-3.21

 

GA+AA

39(19)

35(11)

   

rs1205

CC+CT

134(64)

238(73)

0.0040

1.82

1.21-2.73

 

TT

76(36)

89(27)

   

rs20541

TT+CT

99(47)

189(58)

0.0450

1.47

1.01-2.13

 

CC

111(53)

138(42)

   
  1. * Logistic regression analysis was adjusted by potential confounders including age, gender, smoking history.