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Table 1 Physical and biochemical characteristics of the study subjects divided into insulin-sensitive and -resistant groups on the basis of their median whole-body insulin sensitivity

From: Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

  Microarray qPCR
  Insulin Sensitive Insulin Resistant pvalue Insulin
Sensitive
Insulin Resistant pvalue
n 5 5 - 11 9 -
Age (years) 33 ± 6 39 ± 5 NS 32 ± 4 39 ± 3 NS
Body weight (kg) 60 ± 4 90 ± 5 0.009 69 ± 4 90 ± 5 0.003
BMI (kg/m2) 22.0 ± 0.7 32.5 ± 1.7 0.009 24.7 ± 1.1 33.0 ± 2.0 0.002
Whole-body fat (%) 24 ± 3 36 ± 1 0.009 28 ± 2 36 ± 1 0.002
Fat mass (kg) 15 ± 2 33 ± 3 0.009 20 ± 2 35 ± 4 0.003
Waist-to-hip ratio 0.86 ± 0.02 0.93 ± 0.02 0.047 0.86 ± 0.01 0.91 ± 0.01 0.03
fP-glucose (mmol/l) 5.0 ± 0.1 5.7 ± 0.2 0.016 5.1 ± 0.1 5.6 ± 0.2 0.012
fS-insulin (mU/l) 3 ± 0.5 11 ± 2 0.009 3 ± 0.4 10 ± 1 < 0.001
fS-LDL cholesterol (mmol/l) 2.2 ± 0.2 3.1 ± 0.2 0.016 2.2 ± 0.2 3.1 ± 0.2 0.004
fS-triglycerides (mmol/l) 0.9 ± 0.2 1.3 ± 0.2 0.076 0.78 ± 0.1 1.4 ± 0.2 0.002
fS-HDL cholesterol (mmol/l) 1.9 ± 0.09 1.4 ± 0.05 0.009 1.8 ± 0.08 1.4 ± 0.09 0.003
fS-C-peptide (nmol/l) 0.4 ± 0.03 0.8 ± 0.01 0.009 0.4 ± 0.03 0.8 ± 0.08 0.002
  1. Data are mean ± SEM, fP = fasting plasma, fS = fasting serum