Table 2 Ten most up-regulated pathways in insulin-resistant compared to insulin-sensitive group after an overnight fast
GO category | Pathway name | Nominal p | Permuted p |
|---|---|---|---|
GO:0006954 | inflammatory response | 2.0E-10 | 0.0001 |
GO:0007626 | locomotory behavior | 2.8E-09 | 0.0001 |
GO:0007610 | behavior | 4.5E-09 | 0.0001 |
GO:0002682 | regulation of immune system process | 4.1E-08 | 0.0001 |
GO:0050778 | positive regulation of immune response | 1.0E-07 | 0.0001 |
GO:0055080 | cation homeostasis | 1.4E-07 | 0.0001 |
GO:0002253 | activation of immune response | 1.5E-07 | 0.0001 |
GO:0006968 | cellular defense response | 1.6E-07 | 0.0001 |
GO:0042330 | taxis/chemotaxis | 1.8E-07 | 0.0001 |
GO:0002684 | positive regulation of immune system process | 2.3E-07 | 0.0001 |