Table 3 Ten most up-regulated pathways in insulin-resistant compared to insulin-sensitive group during euglycemic hyperinsulinemic conditions
GO category | Pathway name | Nominal p | Permuted p |
|---|---|---|---|
GO:0001934 | positive regulation of protein amino acid phosphorylation | 6.70E-08 | 0.0001 |
GO:0000904 | cell morphogenesis during differentiation | 1.62E-07 | 0.0001 |
GO:0048675 | axon extension | 2.63E-07 | 0.0001 |
GO:0006954 | inflammatory response | 3.71E-07 | 0.0001 |
GO:0005764 | lysosome | 6.78E-07 | 0.0001 |
GO:0010562 | positive regulation of phosphorus metabolic process | 7.14E-07 | 0.0001 |
GO:0005773 | vacuole | 7.18E-07 | 0.0001 |
GO:0002682 | regulation of immune system process | 1.02E-06 | 0.0001 |
GO:0006955 | immune response | 1.6E-07 | 0.0001 |
GO:0001932 | regulation of protein amino acid phosphorylation | 1.8E-07 | 0.0001 |