Table 4 Ten most down-regulated pathways in insulin-resistant compared to insulin-sensitive group after an overnight fast
GO category | Pathway name | Nominal p | Permuted p |
|---|---|---|---|
GO:0032787 | monocarboxylic acid metabolic process | 5.6E-06 | 0.0001 |
GO:0055114 | oxidation reduction | 9.7E-06 | 0.0003 |
GO:0006066 | cellular alcohol metabolic process | 1.4E-05 | 0.0005 |
GO:0008131 | amine oxidase activity | 2.6E-05 | 0.0002 |
GO:0006631 | fatty acid metabolic process | 5.8E-05 | 0.0012 |
GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors | 1.0E-04 | 0.0003 |
GO:0006725 | cellular aromatic compound metabolic process | 1.2E-04 | 0.0022 |
GO:0006642 | triacylglycerol mobilization | 1.5E-04 | 0.0001 |
GO:0042594 | response to starvation | 2.1E-04 | 0.0012 |
GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors | 2.5E-04 | 0.002 |