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Table 5 Ten most down-regulated pathways in insulin-resistant compared to insulin-sensitive group during euglycemic hyperinsulinemic conditions

From: Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

GO category Pathway name Nominal p Permuted p
GO:0005746 mitochondrial respiratory chain 9.7E-06 0.0002
GO:0044429 mitochondrial part 1.3E-05 0.001
GO:0022900 electron transport chain 1.6E-05 0.0002
GO:0050890 cognition 2.6E-05 0.0005
GO:0016651 oxidoreductase activity, acting on NADH or NADPH 3.9E-05 0.0002
GO:0005759 mitochondrial matrix 4.9E-05 0.0008
GO:0031349 positive regulation of defense response 7.3E-05 0.0008
GO:0022891 substrate-specific transmembrane transporter activity 8.9E-05 0.0022
GO:0003954 NADH dehydrogenase activity 1.0E-04 0.0023
GO:0055114 oxidation reduction 1.1E-04 0.0037