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Table 1 Correlations of plasma adiponectin with the other MetS phenotypes in our cohort

From: A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation

  Phenotype Correlation p-value Inter-correlation (ρ)
Body composition Weight, kg 7.37×10-17 −0.29
Height, cm 0.030 −0.08
BMI, kg/m2 4.22×10-16 −0.29
Waist circumference (WC), cm 1.90×10-22 −0.34
Hip circumference (HC), cm 4.80×10-16 −0.29
Waist to Hip ratio (WHR) 0.000025 −0.15
Total Fat Mass (Fatkg), kg 0.00078 −0.17
Total Fat Mass (Fatpct),% 0.032 −0.11
Total Lean Mass (Leankg), kg 0.00013 −0.20
Total Lean Mass (Leanpct), % 0.026 0.11
Subcutaneous Fat (SubQF), g 0.0012 −0.18
Visceral Fat (VF), g 2.04×10-8 −0.30
Total Abdominal Fat (TAF), g 0.000039 −0.23
Respiratory Quotient (RQ) 0.78 0.02
Resting Energy Expenditure (REE), kcal/24 hrs 8.15×10-7 −0.26
REE/weight, kcal/24hrs/kg 0.29 0.06
  REE/Lean mass (REE/LM), kcal/24hrs/kg 0.16 −0.08
Insulin responsiveness Fasting Glucose (FG), mmol/l 0.00078 −0.12
Fasting Insulin (FI),pmol/l 8.85×10-8 −0.18
Insulin/glucose (IGR) 6.63×10-6 −0.15
Homeostasis model assessment (HOMA) 3.40×10-8 −0.19
Insulin Sensitivity (SI), (× 10-4/min/μU/ml) 1.28×10-6 0.26
Glucose Effectiveness (SG), min-1 0.068 0.10
Acute Insulin Response to glucose (AIRG), μU/ml × 10min 0.45 −0.04
  Disposition Index (DI), AUC (Insulin0-10 min) × SI 0.012 0.14
Lipids/lipoprotein profiles Triglycerides (TG), mmol/l 1.30×10-8 −0.20
Total Cholesterol (TC), mmol/l 0.50 −0.02
LDL-cholesterol (LDL-c), mmol/l 0.42 −0.03
Calculated LDL-C (cal. LDL-c), mmol/l 0.92 0.00
HDL-cholesterol (HDL-c), mmol/l 5.17×10-12 0.25
HMED, nm 0.000020 0.18
LMEDn, nm 0.000851 0.14
LDLppd, nm 4.43×10-6 0.19
  BMED, nm 0.058 0.08
Cardiovascular performance Systolic Blood Pressure (sBP), mmHg 1.55×10-6 −0.16
Diastolic Blood Pressure (dBP), mmHg 0.0071 −0.09
  Pulse, beats/min 0.023 −0.08
Adipokine and cytokines Leptin, ng/ml 5.64×10-11 −0.23
TNF-alpha, pg/ml 0.24 0.04
Interleukin-1 beta (IL-1β), pg/ml 0.89 0.01
  Interleukin-6 (IL-6), pg/ml 0.81 −0.01
  1. The pair-wise intercorrelation (ρ) and its respective significance (p-value) between plasma adiponectin levels and each of the other MetS phenotypes are shown. Inter-correlations that passed the nominal significance cutoff (p<0.05) are depicted in bold italic.