Table 1 Interactions between HIV-1 proteins and 9 “key regulatory” genes
Profiles | Genes | HIV-1 proteins | Mode of interactions |
|---|---|---|---|
Bup | FN1 | Env | binds |
Gag-Pol | cleaves | ||
Tat | competes with, modulated by, up-regulates | ||
Nef | up-regulates | ||
LAMB3 | Tat | up-regulates | |
MYH10 | Gag-Pol | cleaves | |
TGM5 | Env | interacts with, modified by | |
VEGFA | Env | modulates | |
Tat | cooperates with, induces release of | ||
Bdown | PRKCZ | Env | interacts with, inhibits, regulated by, up-regulates |
Gag-Pol | inhibited by, phosphorylated by | ||
Tat | Activates, regulated by, phosphorylated by | ||
PdownBup | FLJ22814 | Nef | up-regulates |
PupBdown | MGAT5B | Env | processed by |
SMPD3 | Env | activates |